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Substance P belongs to the tachykinin family which excites neurons, provoke behaviorial responses, are potent vasodilators and secretagogues.
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Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is fu
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Fumarate hydratase (FH) is an enzyme that catalyzes the formation of malate from fumarate. FH also acts as a tumor suppressor. Defects in FH arer the cause of multiple leiomyomatosis, a growth of beni
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